SARS-CoV-2 Spike Glycoprotein Delta Variant (B.1.617.2, Indian origin) mRNA, with inactivated furin site

Catalog #: EG-347

Size	Catalog #	Price	Add to Cart
ARCA 20 µg	—	$580.00
ARCA 100 µg	—	$1980.00
ARCA 1 mg	—	$15000.00
Cleancap 20 µg	—	$780.00
CleanCap 100 µg	—	$2650.00
CleanCap 1 mg	—	$20100.00
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Product Description

Product Name	SARS-CoV-2 Spike Glycoprotein Delta Variant (B.1.617.2, Indian origin) mRNA, with inactivated furin site
Description	This modified mRNA encodes the full-length SARS-CoV-2 spike glycoprotein B.1.617.2 India origin delta variant, with furin site mutated to PRRD
Features	5' Cap: Capped with ARCA (Anti Reverse Cap Analog, m7(3'-O-methyl)-G(5')ppp(5')G, Cap 0) or CleanCap AG (m7G(5')ppp(5')(2'OMeA)pG, Cap 1) 5’-UTR: derived from human alpha-globin RNA with an optimized Kozak sequence Codon Optimization: Human Mutations: T19R, T95I, G142D, ∆F157+∆R158, E156G, L452R, T478K, D614G, P681R, D950N, P681R, R683A, R685A, D950N Nucleotide Modifications: mRNA modified with both Pseudo-UTP and 5mCTP 3’-UTR: comprises two sequence elements derived from the amino-terminal enhancer of split (AES) mRNA and the mitochondrial encoded 12S ribosomal RNA to confer RNA stability and high total protein expression. PolyA: 180 nt
Sequence	Available upon request.
Application	Animal Vaccine Research (Not for human use)
Concentration	~1 µg/µl
Transfection Protocol	Lipofectamine™ MessengerMAX™ Transfection Reagent Protocol
QC	Agarose gel electrophoresis
Shipping	Dry ice
Storage	-80 oC

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