Murine Leukemia Virus (MLV) Pseudotyped with SARS-CoV-2 Spike Glycoprotein

Catalog #: EG-345

Qty:

Product Name	Murine Leukemia Virus (MLV)Pseudotyped with SARS-CoV-2 Spike Glycoprotein, HexaPro Stabilized Trimer
Description	Murine leukemia retrovirus (MLV) particles pseudotyped with SARS‑CoV‑2 spike glycoprotein, with hexaPro mutations so the surface protein antigenically optimal pre-fusion conformation, produced and purified from HEK 293 cells
Mutations	Furin site RRAR mutated to GSAS; HexaPro mutations (K986P, V987P, F817P, A892P, A899P and A942P) to ensure the S glycoprotein remains in an antigenically optimal pre-fusion conformation
Source	HEK293T cells
Reporter	EGFP
Application	Screening of SARS‑CoV‑2 neutralizing antibodies Assessment of vaccine efficacy
Titer	> 1 X 10⁷ RFU/ml or > 1 X 10⁵ TU/ml
Shipping	Dry ice
Storage	-80 oC
References	Murine Leukemia Virus (MLV)-based Coronavirus Spike-pseudotyped Particle Production and Infection. Bio Protoc. 2016 Dec 5; 6(23): e2035. doi:10.21769/BioProtoc.2035 Retroviral vectors pseudotyped with severe acute respiratory syndrome coronavirus S protein doi: 10.1128/JVI.78.17.9007-9015.2004. PubMed: 15308697

Home \| Privacy Policy \| Terms & Conditions \| Online Price Policy \| Shipping & Return