Log In
|
Shopping Cart
|
Advanced Search
Home
Career
Distributors
Contact Us:
Email: crm@excellgen.com
Products
Modified mRNA
Encapsulated mRNA
mRNA Enzyme
SARS-CoV-2
Pseudovirus
Popular Products
Cancer Proteins
Antibodies
DNA Binding Proteins
Electrophoresis
Genome Engineering
Polymerases
Recombinases
Transcription Factors
Transfection
Services
Modified mRNA
Custom Cloning
Virus Production
Protein Purification
Protein Expression
Pseudovirus
Previous
Return to List
Next
Murine Leukemia Virus (MLV) Pseudotyped with SARS-CoV-2 Spike Glycoprotein
Catalog #:
EG-345
Qty:
Product Name
Murine Leukemia Virus (MLV)Pseudotyped with SARS-CoV-2 Spike Glycoprotein, HexaPro Stabilized Trimer
Description
Murine leukemia retrovirus (MLV) particles pseudotyped with SARS‑CoV‑2 spike glycoprotein, with hexaPro mutations so the surface protein antigenically optimal pre-fusion conformation, produced and purified from HEK 293 cells
Mutations
Furin site RRAR mutated to GSAS; HexaPro mutations (K986P, V987P, F817P, A892P, A899P and A942P) to ensure the S glycoprotein remains in an antigenically optimal pre-fusion conformation
Source
HEK293T cells
Reporter
EGFP
Application
Screening of SARS‑CoV‑2 neutralizing antibodies
Assessment of vaccine efficacy
Titer
> 1 X 10
7
RFU/ml or > 1 X 10
5
TU/ml
Shipping
Dry ice
Storage
-80 oC
References
Murine Leukemia Virus (MLV)-based Coronavirus Spike-pseudotyped Particle Production and Infection. Bio Protoc. 2016 Dec 5; 6(23): e2035.
doi:10.21769/BioProtoc.2035
Retroviral vectors pseudotyped with severe acute respiratory syndrome coronavirus S protein
doi: 10.1128/JVI.78.17.9007-9015.2004
. PubMed: 15308697
Ask a Question
Home
|
Privacy Policy
|
Terms & Conditions
|
Online Price Policy
|
Shipping & Return
Copyright © 2007-2022 Excellgen, Inc. All rights reserved
